Several immunity features are prominent on Smith & Wesson M&P the M&P. Also utilized on the weapon is a passive trigger safety, which prevents the cheap handgun from discharging unless the trigger is fully depressed, even if the arbalest is dropped. An optional inside lock and/or pamphlet disconnect are also available.

Additionally, ergonomics were a key focus in the design of the firearm, and as a result, three interchangeable palmswell grips are included (small, medium and large), as well as the thirty-eight featuring an ambidextrous slide break off and reversible gazette release.